Beyond the antimicrobial activity and contact times for the disinfectant, we encourage you select a product for which your staff will not have to compromise safety for efficacy. By enabling the use of the product with lower risk, staff may be more willing to use it, which facilitates more consistent use, while reducing the risk of worker related injuries and the cost of PPE. Ensuring that staff is compliant with cleaning and disinfection protocol reduces your risk of HAIs and readmissions. Qualifying a product that is responsible has several components, including toxicity, flammability, personal protective equipment (PPE), and compatibility. The product should be nontoxic and should not cause any harm to users, patients, and visitors. The toxicity ratings for disinfectants are danger, warning, caution, and none. The facility should ideally choose a product with the lowest toxicity rating. In addition, one should check the safety data sheet (SDS) for the product’s flammability rating and select the product with the lowest flammability rating. The disinfectant label should contain information on what PPE is required when using the product. Most facilities would prefer a product that requires the least PPE but still offers the staff complete protection from exposure to adverse health effects. Facilities should select disinfectants with an acceptable compatibility profile to ensure that they will not cause damage during routine use to common healthcare surfaces, such as plastic, stainless steel, and other materials.